850 research outputs found

    Out of the Shadows: Undocumented Children’s Access to Education in the United States and Germany

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    Article published in the Michigan State International Law Review

    Optimal Time Utility Based Scheduling Policy Design for Cyber-Physical Systems

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    Classical scheduling abstractions such as deadlines and priorities do not readily capture the complex timing semantics found in many real-time cyber-physical systems. Time utility functions provide a necessarily richer description of timing semantics, but designing utility-aware scheduling policies using them is an open research problem. In particular, optimal utility accrual scheduling design is needed for real-time cyber-physical domains. In this paper we design optimal utility accrual scheduling policies for cyber-physical systems with periodic, non-preemptable tasks that run with stochastic duration. These policies are derived by solving a Markov Decision Process formulation of the scheduling problem. We use this formulation to demonstrate that our technique improves on existing heuristic utility accrual scheduling policies

    Conceptual mechanization studies for a horizon definition spacecraft attitude control subsystem, phase A, part II, 10 October 1966 - 29 May 1967

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    Attitude control subsystem for spin stabilized spacecraft for mapping earths infrared horizon radiance profiles in 15 micron carbon dioxide absorption ban

    Scheduling Design with Unknown Execution Time Distributions or Modes

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    Open soft real-time systems, such as mobile robots, experience unpredictable interactions with their environments and yet must respond both adaptively and with reasonable temporal predictability. Because of the uncertainty inherent in such interactions, many of the assumptions of the real-time scheduling techniques traditionally used to ensure predictable timing of system actions do not hold in those environments. In previous work we have developed novel techniques for scheduling policy design where up-front knowledge of execution time distributions can be used to produce both compact representations of resource utilization state spaces and efficient optimal scheduling policies over those state spaces. This paper makes two main contributions beyond our previous work, to the state of the art in scheduling open soft real-time systems: (1) it shows how to relax the assumption that the entire distribution of execution times is known up front, to allow online learning of an execution time distribution during system run-time; and (2) it shows how to relax the assumption that the execution time of a system action can be characterized by a single distribution, to accommodate different execution time distributions for an action being taken in one of multiple modes. Each of these contributions allows a wider range of system actions to be scheduled adaptively and with temporal predictability, which increases the applicability of our approach to even more general classes of open soft real-time systems

    Mapping Water Availability, Cost and Projected Consumptive Use in the Eastern United States with Comparisons to the West

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    The availability of freshwater supplies to meet future demand is a growing concern. Water availability metrics are needed to inform future water development decisions. Furthermore, with the help of water managers, water availability was mapped for over 1300 watersheds throughout the 31-contiguous states in the eastern U.S. complimenting a prior study of the west. The compiled set of water availability data is unique in that it considers multiple sources of water (fresh surface and groundwater, wastewater and brackish groundwater); accommodates institutional controls placed on water use; is accompanied by cost estimates to access, treat and convey each unique source of water, and; is compared to projected future growth in consumptive water use to 2030. Although few administrative limits have been set on water availability in the east, water managers have identified 315 fresh surface water and 398 fresh groundwater basins (with 151 overlapping basins) as Areas of Concern (AOCs) where water supply challenges exist due to drought related concerns, environmental flows, groundwater overdraft, or salt water intrusion. This highlights a difference in management where AOCs are identified in the east which simply require additional permitting, while in the west strict administrative limits are established. Although the east is generally considered water rich roughly a quarter of the basins were identified as AOCs; however, this is still in strong contrast to the west where 78% of the surface water basins are operating at or near their administrative limit. There was little effort noted on the part of eastern or western water managers to quantify non-fresh water resource

    Pharmacology of DB844, an orally active aza analogue of pafuramidine, in a monkey model of second stage human African trypanosomiasis

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    Novel drugs to treat human African trypanosomiasis (HAT) are still urgently needed despite the recent addition of nifurtimox-eflornithine combination therapy (NECT) to WHO Model Lists of Essential Medicines against second stage HAT, where parasites have invaded the central nervous system (CNS). The pharmacology of a potential orally available lead compound, N-methoxy-6-{5-[4-(N-methoxyamidino) phenyl]-furan-2-yl}-nicotinamidine (DB844), was evaluated in a vervet monkey model of second stage HAT, following promising results in mice. DB844 was administered orally to vervet monkeys, beginning 28 days post infection (DPI) with Trypanosoma brucei rhodesiense KETRI 2537. DB844 was absorbed and converted to the active metabolite 6-[5-(4-phenylamidinophenyl)-furanyl-2-yl]-nicotinamide (DB820), exhibiting plasma C(max) values of 430 and 190 nM for DB844 and DB820, respectively, after the 14th dose at 6 mg/kg qd. A 100-fold reduction in blood trypanosome counts was observed within 24 h of the third dose and, at the end of treatment evaluation performed four days post the last drug dose, trypanosomes were not detected in the blood or cerebrospinal fluid of any monkey. However, some animals relapsed during the 300 days of post treatment monitoring, resulting in a cure rate of 3/8 (37.5%) and 3/7 (42.9%) for the 5 mg/kg×10 days and the 6 mg/kg×14 days dose regimens respectively. These DB844 efficacy data were an improvement compared with pentamidine and pafuramidine both of which were previously shown to be non-curative in this model of CNS stage HAT. These data show that synthesis of novel diamidines with improved activity against CNS-stage HAT was possible

    3 W of single-frequency output at 532 nm by intracavity frequency doubling of a diode-bar-pumped Nd:YAG ring laser 3 W of single-frequency output at 532 nm by intracavity frequency doubling of a diode-bar-pumped Nd:YAG ring laser

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    A beam-shaped 20W diode-bar has longitudinally pumped a Nd:YAG laser in a ring configuration. Unidirectional single-frequency operation is enforced by a Faraday rotator. Intracavity frequency doubling, using a KTP crystal has produced 3W of stable, single-frequency TEMoo output at 532nm
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